Age-related macular degeneration (AMD) is a disease of aging that is:
- common
- gradual
- progressive
- painless
- characterized by deterioration of the macula, a small area in the center of the retina
When unmonitored and untreated, AMD results in vision loss, especially for daily tasks like driving, reading, etc. With appropriate monitoring and timely treatment, most patients can maintain vision for years to come.
Age-related macular degeneration affects the macula region of the retina.
What is the Retina?
- If the eye were a camera, the retina would be the film of that camera
- The retina is a thin sheet of nerve cells that lines the inside back wall of the eye
- Light travels through the eye and ultimately reaches photoreceptors, the light-sensitive cells in the retina
- The signal from the photoreceptors then travel along the optic nerve to the brain, where the signals are interpreted as vision
What is the Macula?
- The macula is the center region of the retina
- The macula is responsible for high detail vision, central vision, reading, etc. The rest of the retina is responsible for peripheral vision.
- AMD affects the macula, and in turn, results in decreased vision for tasks like reading, driving, recognizing faces, etc.

What are the Symptoms of AMD?
What are the Types of AMD?
There are 2 types of AMD
- Dry age-related macular degeneration (dry AMD)
- Milder, earlier, more common form of AMD
- Age-related deposits accumulate in the retina, causing mild to moderate vision symptoms
- In late stages, tissue loss (called “atrophy” or “geographic atrophy”) can occur, resulting in severe vision loss
- The dry form can convert to the wet form at any time
- Wet age-related macular degeneration (wet AMD, also known as exudative AMD)
- Wet AMD has all the features of dry AMD, plus:
- New blood vessels that grow under and/or into the retina. This abnormal blood vessel growth is called “choroidal neovascularization.”
- The abnormal blood vessels leak fluid or blood into the retina, thus “wet” AMD
- Vision decrease may occur gradually or it can occur suddenly, with potentially vision loss
- Wet AMD has all the features of dry AMD, plus:



What are Risk Factors for AMD?
- Older age
- Female
- Caucasian
- Family history
- Smoking
- High cholesterol
- High blood pressure
How Does My Doctor Diagnose AMD?
- Dilated retinal examination
- Optical coherence tomography (OCT) scan: painless photograph that provides a cross-sectional scan through the macula so that microscopic details of the macula can be discerned

In some patients:
- Fluorescein angiography
- A dye is injected into the arm, from which to travels through the blood to the eye.
- Photographs are taken of the eye which map out all the blood vessels and blood flow in the retina
- This test identifies areas of blood flow loss as well as areas of new blood vessel grown (neovascularization)

How is Dry AMD Treated?
- Patients with dry AMD are monitored for conversion to wet AMD (for which there is treatment, see below).
- AREDS2 vitamins (over the counter) may reduce progression of dry AMD and thus may be recommended
- An “Amsler grid” is provided to allow patients to monitor for subtle vision changes between appointments
- If there is geographic atrophy present, treatments are now available to slow down the progression of geographic atrophy (Syfovre, Izervay)
How is Wet AMD Treated?
- Wet AMD is treated with injections of medications (anti-VEGF medications) that block VEGF.
- VEGF causes abnormal blood vessel growth and blood vessel leakage; thus, anti-VEGF agents reduce leaking from abnormal blood vessels and can even promote regression of abnormal blood vessels
- There are several anti-VEGF medications
- Avastin (bevacizumab)
- Lucentis (ranibizumab)
- Eylea (aflibercept)
- Vabysmo (faricimab), which not only blocks VEGF but also blocks Ang2 which is involved in AMD
- And others
What is it Like to Get Intravitreal Injections in the Eye?
- The injections are given into the eye (intravitreal injections) in the office, after drops are given to numb and clean the ocular surface.
- The medications last several weeks in the eye.
- Some patients require injections every month to control the disease, while others require injections less often, and yet others are able to eventually stop injections and monitor for recurrence.
- The treatment is individualized to each patient’s disease and response to treatment.
- There are new drugs in the research pipeline that may last longer.
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Patient Reviews
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Roz Cole0 days agoTrustindex verifies that the original source of the review is Google.
Prompt & efficient.Posted on Google![]()
Andy Shields0 days agoTrustindex verifies that the original source of the review is Google.
Professional officePosted on Google![]()
PBofLN0 days agoTrustindex verifies that the original source of the review is Google.
I’ve been seeing Dr. Eifreg for a number of years now since he reattached my almost completely detached retina. He is an excellent doctor and surgeon. He never rushes me through my appointments and answers any questions I have. In addition, he is personable, can be funny, and is just a very nice man. From the front office staff to the assistants who check your eyes before you see Dr, Eifreg, they are all extremely efficient. I am now on yearly maintenance visits and they always contact my insurance for a referral before my appointment. I also always get an appointment reminder text or call. But what’s really amazing - This is a VERY busy practice and I am always seen on time or within maybe 15 mins of my appointment time. I don’t know how they do it, but this office runs like a well-oiled machine. And to top it off, EVERYONE is helpful, cheerful and has a “service” attitude at all times. I know this all sounds too good to be true, but it is honestly the case at Dr. Eifreg’s office. I am so glad my primary doctor sent me to Dr. Eifreg for my retina surgery. Of course the most important thing is that he’s an excellent surgeon, but it’s also wonderful that he runs a great office with an exceptional staff!Posted on Google![]()
Deb Hanna0 days agoTrustindex verifies that the original source of the review is Google.
Everyone at this office was very friendly. The office was definitely busy but It was my first visit there and they still made me feel welcome and cared for. Dr Gupta explained my condition so I could easily understand it and was very pleasant to talk with. I had to leave another Retina group because of an insurance change but think the transition to this new group went smoothly and will be a good fit for me moving forward.Posted on Google![]()
Diane Bridges0 days agoTrustindex verifies that the original source of the review is Google.
Very efficient and pleasant staff. Excellent doctor. Have been going to him for nine years. I would never change doctors!Posted on Google![]()
PriscillA Schultz0 days agoTrustindex verifies that the original source of the review is Google.
everyone is very kind and thorough in the office. The doctor is great and was on time.Posted on Google![]()
rebecca peyrefitte0 days agoTrustindex verifies that the original source of the review is Google.
This experience at this Dr office was outstanding. All the staff was very supportive and efficient. I was very pleased with the service I was given.Posted on Google![]()
Deborah Misserville0 days agoTrustindex verifies that the original source of the review is Google.
The Best! Professional and knowledgeable of current medical technology and techniques. And equally as important...kind and caring Dr and staff!Posted on Google![]()
Juli White4 days agoTrustindex verifies that the original source of the review is Google.
Efficient and considerate of the patient’s time, friendly and most importantly, competent - everything you’d want from a doctor’s appointment!Posted on Google![]()
Kelvin Kitaoka (Kazu)5 days agoTrustindex verifies that the original source of the review is Google.
Great Organization and very methodical with service and procedure. Dr. Chen is the best in Retina eye care.. hands down.


